The relevance of the vaccine problem was previously exacerbated by the rising proportion of children with autism spectrum disorders. But since last autumn, all these concerns about autism simply erased measles outbreaks in the world (including in Lithuania).
But let's start from the beginning. Out of conspiracy. Was? Opponents of the vaccine (shortly) will be enthusiastic, some scientists (in short) will be bitter, but the answer to this question is clear and clear YES. The only conspiracy was not only pharmacists but more doctors and more lawyers.
It all started with a conspiracy
Andrew Wakefield has heard people who have at least a little more vaccine and autism. This is the first doctor who, along with 12 colleagues, has proven the relationship between measles, mumps and rubella (MMR) and autism in a three-way study. In 1998, the highly respected scientific journal The Lancet published a complete study on the medical and supermassive world. This is A.Wakefield, who is the man who basically started the entire movement against wax.
Unfortunately, fame did not last long. After a more detailed analysis of the contents of the study report, it turned out that twelve children (supposed to have a sample size in themselves) – Wakefield were targeted, without random control. The scientist used inappropriate methods of investigation. The worst thing is that the scientist had a direct financial interest in interfering with the MMR vaccine, because … it was bribed by lawyers who represent parents of children with autism in cases against pharmaceutical companies.
Photo: Irmantas Gelūnas / 15min / Classification before vaccination
Wakefield himself was sad about the end of this story: his publication was a shame and with the greatest noise that was removed from the Lancet database, the doctor himself lost his medical license and left his homeland, the United Kingdom, in the United States. He has become a leader in the field of vaccination and remains among the opponents of vaccine as one of the greatest personalities and celebrities.
But do not be deceived – Wakefield is not a fighter for the truth and health of children. He's a million dollars fighter. A former doctor, together with one of the parents of children in a well-known study, intended to establish a company that would produce diagnostic kits for "autistic colitis" – his own fictional diagnosis. Wakfield himself announced that only 43 million of these lots would be traded. dollars per year. With such a diagnosis of the child, parents could already turn to courts to claim greater benefits from vaccine manufacturers.
In addition, the main purpose of the article was not to publish a global, comprehensive war on all types of vaccines, but to criticize the trivalent MMR vaccine, in the same article, which states that the older monotone vaccine does not cause measles autism in two decades.
Of course, the question may arise: o Is it possible that Mr Wakfield is the only beam of common sense in the world bought by the pharmaceutical industry? Barely. As the journalist Brian Deer has shown, the purchase of one scientist – Wakefield – costs about half a million pounds. Buy thousands of scientists from around the world who carry out safety research in the vaccine cost billions and maybe ten or even hundreds of billions of dollars / dollars / pounds.
For whom is it useful?
Let's get back to the profits for vaccination. The price of one MMR vaccine is already in Lithuania – from 27 to 30 euros. The annual fertility rate in Lithuania is about 30 thousand. Or about 900 thousand. EUR per year for MMR only. Do we support the pharmaceutical industry when we are vaccinated (and not just for measles, but also for influenza, tick-borne encephalitis, hepatitis, tropical infections)? No doubt, yes.
Photo: Sigismund Gedvila / 15min
However, the pharmaceutical industry is not a set of one-day businesses. It is one of the largest companies in the world that calculates its annual income for hundreds of thousands and not more than ten million but a few dozen billion. The creation of one drug for such a company can last a decade or more and costs billions of dollars. Therefore, their goal is not a quick profit. Business plans are developed strategically, with insights that have been for many years. And vaccinations, no matter how strange, are in the long run, do not increase or even reduce the income of these companies.
Why? Because the cost of bringing the patient from the hell door to the door is not $ 30, and many – dozens and hundreds more – more. And if the disease is complicated by the complications of chronic conditions requiring the use of medicines, one patient deserves income for decades. The outbreaks of measles (and encephalitis, hepatitis and tropical diseases), which were hundreds of times greater than in our environment, would be more profitable for such companies.
A recent analysis of the success of pharmaceutical companies has been quite recent: treatment of patients is not worth it. It's much more profitable to treat them all for life.
So why do pharmaceutical companies produce, which undermines their financial performance? The answer is simple. Public interest and competition. If the vaccine is not produced by Merck, they will be manufactured by GSK or Pfizer, and public health authorities will ensure that vaccines are purchased for all that need to be vaccinated.
Where is the distrust to vaccination?
Immediately after the publication of Wakefield in 1998, the frequency of vaccination against the MMR decreased from 92 to 79 per cent. The effect was staggering – 13 percent. parents of children believed in Sarlatan stories. In over ten years, about 92 percent were again reached. Frequency of vaccination, although the World Health Organization states that the target vaccination rate with the MMR is 95%.
For the last two decades, the Internet has been a rather mature network of people who used and disseminated information. With increasing development, its availability becomes easier, with the growing number of sources of information on the Internet becoming the dominant platform, a kind of static democracy that anyone can hold and express. Whatever education, experience, reliable knowledge.
In the long run, the vocabulary of the doctor had even a terrifying expression – Dr. Google. This term describes the type of disorder in which a person without medical education, but with the possibility of turning on the computer, finds a medical diagnosis on his own network, pet or child, and requires the doctor to confirm and treat him according to this diagnosis. Unfortunately, doctors generally agree that in the field of disease diagnosis, no skill in using the Google search engine is equal to ten or even several years of university medical studies.
Pharmaceutical and chemical experts know that Google and other unclear Internet sources can also cause other disorders, such as chemo-phobia, which is described as a fear of chemistry and chemical compounds. It is also driven by various eco-enthusiasts and bio-enthusiasts whose simple (but not necessarily true) language for television and other media channels is more desirable than the boring explanations of scientists with chemistry or closely related fields.
Another reason is the so-called Dunning-Kruger effect: 2011 Psychologist David Dunning has defined and described a phenomenon in which people with large knowledge gaps in a certain field can not recognize the gaps in their knowledge and therefore consider themselves competent in areas where they obviously lacking in expertise.
The overall result of all these three factors is very effective in spreading unreliable and false knowledge that is acceptable to a certain part of society. It is true that in this part of society, people with medical education hardly find it.
And where is autism then?
The second natural question is, what is the cause of the ever more frequent disorder of the autistic spectrum? Unfortunately, scientists still can not give clear and unequivocal answers, but all of the extensive, reliable studies show that there is no link between MMR and autism. There is no connection between autism and other vaccines or commonly used components of the vaccine (timerosal or mercury compounds).
However, there are many reliable scientific articles that contain a long list of factors associated with autism or unrelated factors. Ironically, the latest scientific article on this topic states that one of the causes of congenital autism … is an infectious disease during pregnancy, including those that can be prevented by vaccination.
What are the other side effects?
Since the vaccines are not consecrated with homeopathic water, it should be recognized that they can, like all effective medicines, have undesirable effects. On the other hand, the requirements for clinical and post-clinical testing are also applicable to vaccines, and if the benefits of the product outweigh the benefits, they would be withdrawn from the market.
It is true that vaccine adversaries often often misrepresent that the negative effects of vaccines are hidden from the public. In fact, credible sources of reliable medical information of such information are in one place, systematic and open. One of the best-quality and most suitable sites for treating adverse reactions was developed by US Centers for Disease Control.
Another source of similar information is the World Health Organization website. For example, the latter indicates that localized redness at the site of injection after vaccination is quite common, but not harmful, and it expires in 2-3 days. Up to 15 percent can be vaccinated day or two heat, up to 5 percent. Short-term rashes may occur.
Serious side effects occur much less often. For example, an anaphylactic life-threatening reaction develops between 3.5 and 10 cases per million, with epileptic seizures occurring at approximately 1 in 3,000, and in thrombocytopenia at 1 in 30,000.
Compared to measles vaccination, this disease was almost 100%. children. The latest information from Madagascar is really unhappy: since the beginning of the outbreak in 2018. In September, this disease was diagnosed in almost 87 thousand. of which 1141 died.
Disclosure of Interest: The author of this article is a magister of pharmaceutical sciences, who has no financial and non-financial connections with the pharmaceutical industry and has worked for about half a year in the company Eurovaistine, pharmaceutical marketing.