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E. coli can live in the intestines of women without symptoms



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Virulent and multiresistant strains Escherichia coli women can even thrive in the intestines of women without symptoms, she found a new study.

A group of researchers at the University of Health Sciences in Washington and UW Medicine found that 8.8 percent of healthy women who did not have obvious symptoms of urinary tract infections were carrying a superintendent, Escherichia coli strains in the intestines.

Three-dimensional illustration of Escherichia coli. Credit for the picture: Kateryna Kon / Shutterstock

Three-dimensional illustration of Escherichia coli. Credit for the picture: Kateryna Kon / Shutterstock

Women more prone to urinary tract infection (UTI)

A study published in the journal Clinical Infectious Diseases has shown that the pathogen causing the disease can pass from the gastrointestinal tract of the woman into her urinary tract through the urethra and urinary canal.

The female urine channel is relatively shorter than that of men, which is why it is exposed to urinary tract infections. Bacteria can reach the bladder and other parts of the urinary tract.

Escherichia coli is the most common cause of UTI in women who causes cystitis or inflammation of the bladder. This bacterium is often found in the digestive tract, but now the group has found that it is also a multi-resistant strain in the gut.

Substances resistant to multiple drugs found in human excrement

The researchers analyzed data from over 1,000 healthy women who have no symptoms of urinary tract infection. They have been found to be resistant to fluoroquinolones Escherichia coli 8.8 percent of healthy women, with most of the pathogens belonging to the strain-resistant strain, ST1193 or STI131-H30R clone groups.

ST1193 or STI131-HCloning groups 30R cause most of the urinary tract and drug-resistant blood circulation. Clone groups of superges were also found twice as often in the urine of patients who had them in the intestines.

Even those who had a resistant intestine on fluoroquinolone (Cipro) Escherichia coli he gave urine samples. More than a third of them had a positive test Escherichia coli and 77 percent of them were Cipro-resistant, and the bacterial clone matched the mud pattern.

Without the use of antibiotics in the past

The researchers also studied whether patients during the study took any antibiotic for any type of infection in the body. They found that these women did not take antibiotics and had no symptoms.

Three months after urine collection, 7 percent of 45 who previously had asymptomatic, developed urinary tract infections.

"Two pandemic pathogens that are resistant to fluoroquinolones Escherichia coli found in clinical samples are top colonizers of the gut and there are usually there, "the authors wrote in the study.

"An unusually high proportion can also occur in the urine of healthy women who did not have documented diagnoses of urinary tract infections during sample testing. Both appear to be interconnected, "they added.

Clinical care and infection control

Previously, it was known that most UTIs develop when the bacteria in the intestine find their way into the urethra and urethra in the bladder. However, there is new information that healthy women can combine strains of pathogenic, multidrug-resistant.

The study has numerous consequences for clinical care and infection control. Findings can help prevent urinary tract infections (UTIs) and form new therapies with the fight against supervergings. The ability to detect whether a healthy female resistance to multiple drugs and virulent bacteria in the gut can reduce the prevalence of multi-drug-resistant infections among healthy women who do not even feel any symptoms at all.

Precautionary measures can also reduce the risk that transporters will transfer the pathogen to other individuals in the household.

Researchers emphasize that the ability to determine the pregnancy status of a woman can help predict future resistant infections and form preventive measures to reduce the onset of infection.

The most common drugs prescribed for IMS are fluoroquinolones, but some strains have become increasingly resistant to these drugs. Although efforts have been made to limit the use of these drugs, the proportion of multidrug-resistant infections is spreading throughout the world.

Severi Superduga, ST119 and ST131-H30R, which has been found to remain in the gastrointestinal tract for an unprecedented period and without any symptoms, may have contributed to its widespread occurrence worldwide.

Diary Reference:

Tchesnokova, V., Rechkina, E., Chan, D., Ghirmai, H., Larson L., Ferrier K., Schroeder D., Solyanik T., Shibuya S., Hansen K., Ralston, J., Riddell, K., Scholes, D., and Sokurenko, E. (2019). Pandemic uropathogenic fluoroquinolone-resistant Escherichia coli has an increased ability to persist in the gut and cause bacteriuria in healthy women. Clinical infectious diseases. https://academic.oup.com/cid/advance-article-abstract/doi/10.1093/cid/ciz547/5528138?redirectedFrom=fulltext

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