A group of Chilean scientistsHe's looking for soccer players diagnostic tool andl Alzheimer's disease, which is a growing disease and currently only treats its symptomatology and not its origin, as reported EFE researchers, t
It's an investigationr if there is a collective damage to the players when they are constantly struck with a header they can create dementia or Alzheimer's diseasethe doctor explained Waldo Cerpateam leader.
Through biochemical markers, cognitive tests and images of brain researchers they hope to describe neurodegenerative diseases in order to manage more effective treatment and stop their progress, said Cerpa, future deputy director Center of excellence in biology medicine Magallanes (Cebima)
According to data from. T Alzheimer's professional company and other dementia (Coprad), in Chile 200,000 people are currently suffering from this disease, information that could be truncated by 2050.
At the same time, GFK Adimark's advisory firm found that 14 percent of the Chilean population occasionally plays football with danger, warned. Waldo Cerpa, who suffers permanent blows in his head.
"We are a football country, as children are subjected to this contact sport, where caution is lost and the perception is that the damage accumulates," he said.
"According to existing studies with some markers of injuries, it's not necessary to hold firmly, it's enough to keep your ball constantly in your life to obtain a pre-position for the development of dementia, "said the Center for the Care and Career of the Catholic University of Chile (Care UC).
Project that has supportl National Science and Technology Development Fund (Fondecyt), It will analyze how cumulative damage caused by trauma can degenerate learning and memory functions.
For that, will work with the trade union of professional football players (Sifup) and examine players who have suffered a contusion, along with a neurologist at Catholic University Maximiliano Rovegno.
Both, with the help of a psychologist, will try to find out what correlation exists between headaches and the development of dementia and Alzheimer's disease. Finding these patterns, certain biochemical markers of damage, would allow them to develop for the first time the form of early detection in groups that are more at risk.
In addition, Cerpa in Cebima is seeking treatment for the disease by administering lithium or other compounds of natural origin existing in the Magallanes region.
In her career, the Cerpa studied glutamate, which is the most important neuronal portable brain molecule, a medium for which approximately 80 percent of the synapses (specialized intracellular functional approach among neurons) of the central nervous system are produced. .
Thank youl glutamate, travels sensory, motoric, cognitive or emotional information as wells that it is the original actor in the storage and restoration of our memories and that its effects are mostly performed through its receptors located at the synaptic level.
Among them, the receiver stands out N-methyl-D-aspartate (NMDA), which changes in diseases such as Alzheimer's or Parkinson's disease.
The Cerpa studied how the NMDA receptors behave in two conditions of damage occurring in the brain: oxidative stress and non-group processes, elements found in every degenerative neurological pathology and also in acute diseases, i.e. with a blow to the head.
In the study, the team will be able to analyze, insofar as these mechanisms are activated, how they are modified, and how they contribute to the progress of cognitive impairment, and more so if they succeed in finding out how they are changed they will also be able to identify therapeutic elements that enable these same mechanisms .
Waldo Cerpa believes that work should allow not only a look at the stroke-related injuries, but also the entire battery of cognitive analysis, which will allow us to say whether the person has, in addition to injury, an increase in oxidative and neuroinflammatory markers.
In this context, analysis with soccer players could identify these markers before developing chronic pathology and taking preventive measures.