Can a blood test help detect Alzheimer's disease?


According to an investigation carried out by scientists Conicet in Leloir Institute Foundation (FIL), A blood test can help detect early Alzheimer's disease, a neurodegenerative disease that suffers more than half a million Argentines.

Various experimental demonstrations in patients and animal models of this pathology show that glucose consumption in the affected brain is reduced, which is an essential source of energy for neurons. Scientists have come to the conclusion that that it can change in platelets, one of the blood components responsible for the coagulation and repair of vessels.

"Platelets could reflect the lack of energy and the processes of inflammatory and oxidative stress in the brain of patients with Alzheimer's disease"said Dr. Laura Morelli, director of the study and a member of the laboratory for amyloidosis and neurodegeneration at FIL.

"We made isolation of platelets from the blood (in rats) in the laboratory and determined the ability of mitochondria to consume oxygen and generate energy." The mitochondrial group worked less, "explained the expert in a dialogue with Telam.

"These results provide use of platelets as indicators of brain energy function. This determination would help to peripherally reflect what is happening at the central level in the body, and this is added to other specific analyzes can identify an early diagnosis of Alzheimer's disease"revealed Morelli."

Finally, the doctor mentioned whether in the near future this pioneering review could turn into a routine analysis in humans: "Generally, everything that works well for the heart is good for the brain, but the reality is no special treatment or medicine for Alzheimer's disease, so we focus on improving the quality of life of the patient. Still the lack of this study becoming a routine analysis, but it is very important to discover biological markers or indicators that enable us to treat Alzheimer's in time in humans.

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