Emperor orders have a lower level of "good" intestinal bacteria, says Science



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Cesarean babies slowly acquire certain types of "good bacteria" in the intestine and have a higher degree of potentially problematic bacteria than those born in vaginal, researchers say.

A study of over 100 babies showed that vaginal births had a very different composition of intestinal microbial (a cluster of intestinal microorganisms), causing imperial orders more prone to respiratory infections. Differences were reduced when babies became older.

Previous studies have shown that the delivery method affects the neuromuscular microbiome, and some have said that this is possible because many mothers who have had a caesarean section need antibiotics.

A new study to be presented at the European Congress of Clinical Microbiology and Infectious Diseases in Amsterdam supports claims that differences in this mode are driven primarily by delivery methods.

The study included a group that collected 10-point faeces in a year from 46 infants born with caesarean and 74 infants born vaginally from the first excrements and analyzing the microbial composition.

It is important that the group says that antibiotics, if necessary, were given only to mothers when the baby was delivered – meaning that babies were not directly exposed to antibiotics.

Results based on sludge analysis in mothers and infants also showed that babies born with Caesarean section were slowly gaining some "good bacteria" that were important for digestion of milk, and had higher levels of some types of potentially harmful bacteria like those born vaginal.

"We believe that delivery methods are an important driver or modifier of intestinal microbials in young infants," said Debby Bogaert, professor at the University of Edinburgh, who participated in a project with colleagues in the Netherlands.

She added that the conclusion was supported by the finding that antibiotics that are given to mothers after childbirth do not affect their own intestinal microbial, and that differences in infant microbiality were also observed in infants who were only fed with a bottle, indicating that the effects were not on infants receiving antibiotics via breast milk.

The group adds that infants with higher levels of potentially harmful bacteria in the first year had multiple respiratory infections.

This, said Bogaert, could help explain why some studies show that children born with caesarean section have a greater risk of respiratory infections.

Another study to be presented at the conference examined whether the microbes found in infant gut were associated with their overweight potential when they were growing up.

A group of researchers from Finland collected drops from 212 newborns, including the first chair after birth, which is thought to occur when the baby is in the womb. The results show that the composition of the microbiome in the first mud of a child is related to whether the child has an overweight age at the age of three years.

Katja Korpela, one of the researchers who participated in a study from the University of Oulu, said that the microbiological composition of the baby's first sludge can be influenced by many factors, including the use of antibiotics during pregnancy and the living environment of the pregnant mother.

However, it is not clear whether the observed link is the cause and effect, or whether the method of mediation affects the results.

"The concept of microbial fetuses is very controversial and the colonization process after birth is better understood as a process of colonization before birth," said Korpela. However, it was interesting that microbiom, which was born before birth, is probably associated with the later health of children.

Tim Spector, a professor of genetic epidemiology at King's College in London and an expert on human microbiology, said that the studies expanded what previously assumed the importance of intestinal microbes early in life.

"One study confirmed large cross sectional studies on the c-section that cause immune problems later in life with an increased risk of infection, and the second suggests that the first microbes of the baby, often coming from the mother, increase the risk of obesity," he said. "If we want to improve their health later in life, we need to treat the health of the gut more seriously."

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